Intestinal microbiome balance

What is the human microbiome? 


The human microbiome is the total of micro-organisms that live together in the human body. It consists of bacteria, fungi, archaea, and viruses, which when in balance are not harmful, but necessary for maintaining good health.


A growing number of studies proves that changes in the composition of the microbiome are related to many conditions of disease. 

Did you know that the total human microbiome has:


More cells
than the human body



More genes
than the human body 


1 kg


Most of the human microbiome is found at the intestine, and more specifically the large intestine 

Colonization of microbes in the gastrointestinal tract 


The biggest numbers of micro-organisms are found in the small and the large intestine. The intestinal microbiome consists of dozens of trillion of micro-organisms, including at least 1,000 different species. 

The intestinal microbiome during lifetime


Its creation begins since the moment of birth, and it is affected by the conditions of labour (kind of labour, environment etc.).

The intestinal microbiome evolves to an important extent during the first two years and is reinforced by breastfeeding. The child’s intestinal microbiome continues getting mature up until the age of 12, when it is completed.

Afterwards it is stabilised, and, under normal circumstances, it remains unchanged for the rest of life.

Nevertheless, a qualitative and quantitative change of the microbiome is seen after the age of 50. The balance between friendly and possibly pathogenic micro-organisms is disrupted, creating conditions that favour diseases.

Age stages in which the intestinal microbiome is formed


Factors that disrupt the intestinal microbiome 

  • antibiotics or other medication
  • smoking and/or overconsumption of alcohol
  • overconsumption of animal products and sugar
  • antibiotics and pesticides, through food of animal and vegetable origin
  • environmental pollution
  • chlorination of water
  • physical and mental strain
  • aging



What are probiotics?


Probiotics are alive micro-organisms which, when received in sufficient quantities, have a positive result in preventing or curing a special pathological condition, through the improvement of the balance of the host’s intestinal microbiome.

These micro-organisms survive during their passage from the upper gastrointestinal system, and they end up in the intestine where they act in a beneficiary way, improving the balance of the intestinal microbiome and contributing to the improvement of one’s health.

What are prebiotics?


Prebiotics are mainly dietary fibers which are used selectively as nutritional substrate by the endogenous bacteria, which colonize the intestinal tract, developing their growth and metabolic activity in a beneficiary way for the host.


A major example of the is inulin,

which is a natural dietary fiber




an innovative approachι 


Combinational preparations of probiotics and prebiotic fibers


They offer collaborative and beneficiary action, granting the benefits of both friendly bacteria and, at the same time, of prebiotics. 

Probiotics and benefits for health


  1. Activation & regulation of immunological functions (homeostasis)
  2. Maintenance & reinforcement of intestinal epithelial barrier
  3. Intestinal action of regulating the nerves
  4. Protective action against pathogenic bacteria
  5. Nutritional benefits

Selection of adequate species & strains of probiotic bacteria 


bacteflora® contain combinations of probiotic species in high concentration with an aimed action, and capable to colonize the individual parts of the digestive tract

  • Bifidobacterium
  • Lactobacillus
  • Lactococcus
  • Streptococcus
  • Enterococcus
  • Propionibacterium


Probiotic strains capable to stick into the intestinal cells


bacteflora® remain in the intestine for longer, providing their benefits.

Through their attachment to the intestinal mucus, they do not allow pathogenic micro-organisms to get attached. 

Adequate proportions and combinational action between the selected strains


Strains that can survive the stomach acids, bile acids, and pancreatic enzymes. 


Micro-encapsulation method
for stability
during storage

Viability of bacteflora®
bacteria through the whole period of storage

Micro-encapsulation Technology


Innovation in packaging

High quality of packaging material bacteflora® for the greatest protection of sensitive micro-organisms.
  • ALU-ALU blister
  • Activ vial
  • Triple layer sachet 
No need to be kept refrigerated. Can be kept at room temperature.

Alu-Alu Blister Package


Multi-layer material with three different materials, that are attached to each other, therefore the bacteflora® products are fully sealed and 100% protected.

The material of the base and the blister cover are made of aluminium foil, and they act as a barrier to humidity, oxygen, and strong light.

It is kept untouched. Due to its processing, it is highly resistant to rips and drillings, maintaining its initial form. 

Activ-vial Package

Two-shot processing. An extra material is used for the package’s interior lining, to guarantee the maximum protection of probiotics.
Every bacteflora® container is sealed with a special aluminium foil and then is closed with a special top, for 100% safe sealing.
Best storage. The package is preserved untouched for a long period of storage under conditions of temperature up to 25°C and humidity up to 60%.

Triple Layer Foil Sachet Package

The bacteflora® sachets κare made from multi-layer material. Three different materials are used, attached to each other, blocking every external factor such as light or humidity.
The package is preserved untouched for long-time storage at room temperature for best storage.

Quality and security certifications of the bacteflora® production 


In OLONEA® we offer the highest quality, effectiveness, and security possible, having obtained all the necessary certifications.  



High security standards.

Stability into bacteflora® quality 


stages of



different measures
for securing quality